Verdadero beneficio de HMB.
Publicado: 03 Dic 2006 22:22
I personally have felt subjective benefits from HMB supplementation. Mostly, a sense of faster recovery and less noticeable “stiffness” in the morning after.
Here is where much of the misunderstanding about HMB comes in. HMB has NOT been shown to directly inhibit protein breakdown, and certainly does not cause protein synthesis. A study done in 1997 looked at the effects of giving lambs high doses of HMB (Br J Nutr. 1997 Jun;77(6):885-96). To their surprise, HMB did not have any effect on protein catabolism or anabolism. In essence, HMB didn’t do squat under normal conditions.
So, if you are expecting HMB to "build" muscle you are going to be disappointed. If the "noticeable effect" you are looking for is anabolism, you are going to be disappointed.
However you’ll notice that the fate of ingested HMB is mainly to be converted to HMG-CoA, a substrate for cholesterol synthesis
It appears that cholesterol synthesis may be a rate-limiting step in membrane repair after intense training.
HMB no tiene ningun efecto sobre catabolismo proteico o anabolismo.
La mitad del HMB consumido se convierte en HMG-CoA,un substrato de síntesis de colesterol...Personalmente veo un beneficio en el HMB,el cual es una sensación de una recuperacion mas rapida y menos agarrotamiento en la mañana siguiente…
Esto aparece que sintesis de colesterol es un factor limitante del reparo de la membrana muscular despues de entrenamiento intenso...
Fuente: http://users.telenet.be/aaitee/HST%20Faq_book.pdf
Here is where much of the misunderstanding about HMB comes in. HMB has NOT been shown to directly inhibit protein breakdown, and certainly does not cause protein synthesis. A study done in 1997 looked at the effects of giving lambs high doses of HMB (Br J Nutr. 1997 Jun;77(6):885-96). To their surprise, HMB did not have any effect on protein catabolism or anabolism. In essence, HMB didn’t do squat under normal conditions.
So, if you are expecting HMB to "build" muscle you are going to be disappointed. If the "noticeable effect" you are looking for is anabolism, you are going to be disappointed.
However you’ll notice that the fate of ingested HMB is mainly to be converted to HMG-CoA, a substrate for cholesterol synthesis
It appears that cholesterol synthesis may be a rate-limiting step in membrane repair after intense training.
HMB no tiene ningun efecto sobre catabolismo proteico o anabolismo.
La mitad del HMB consumido se convierte en HMG-CoA,un substrato de síntesis de colesterol...Personalmente veo un beneficio en el HMB,el cual es una sensación de una recuperacion mas rapida y menos agarrotamiento en la mañana siguiente…
Esto aparece que sintesis de colesterol es un factor limitante del reparo de la membrana muscular despues de entrenamiento intenso...
Fuente: http://users.telenet.be/aaitee/HST%20Faq_book.pdf